MAKE Wellness released a 2025 research report revealing America’s escalating health crisis, including 224% increases in mental health fatalities and 161% rise in overdose deaths. The study proposes AI-enhanced, personalized wellness solutions combining advanced technology with traditional practices to address comprehensive health needs.
America is facing a wellness emergency, and the numbers are staggering. But what if the solution isn't just one thing—what if it's the intelligent integration of cutting-edge technology with time-tested wellness practices?
At MAKE Wellness, we've just released our comprehensive 2025 "Future of Health and Wellness" research report, and the findings reveal both the depth of our current crisis and a clear pathway forward.
Let's be honest about what we're dealing with. The data from authoritative health organizations paints a sobering picture:
Mental Health in Crisis: America's Health Rankings Annual 2024 Report shows us that mental distress-related fatalities have skyrocketed in certain regions—we're talking increases of over 224% in the past decade alone.
The Overdose Epidemic Continues: Drug overdose deaths have climbed 161% from 2010 to 2022, jumping from 12.4 to 32.5 deaths per 100,000 people. And the trajectory isn't slowing down.
But Here's What's Encouraging: Despite these challenges, 82% of American consumers now recognize wellness as essential to their daily lives. People are ready for change—they're just looking for solutions that actually work.
Here's where things get interesting. Recent McKinsey research shows that about 20% of US consumers are actively seeking biometric-driven, personalized health recommendations. We're moving beyond one-size-fits-all approaches to wellness, and technology is making truly individualized care possible.
The World Economic Forum documented $11 billion in venture capital flowing into AI health solutions just last November. This isn't just investment buzz—it's recognition that we're at a tipping point where technology can finally deliver on the promise of personalized healthcare.
Through our research, we've identified what we call a "dual-pathway wellness strategy." It's built on two fundamental pillars:
Advanced Technological Integration: We're talking about AI-enhanced solutions that can analyze your unique biological markers and lifestyle patterns to create truly personalized wellness plans.
Strategic Behavioral Modification: Technology alone isn't enough. Sustainable wellness requires conscious lifestyle adaptations that work with your individual circumstances and goals.
At the heart of our approach are scientifically-validated peptide innovations—molecular signaling compounds that represent a new frontier in wellness support. When you combine these naturally-sourced therapeutic compounds with smart technology and behavioral insights, you create unprecedented opportunities for meaningful health improvements.
As our Chief Marketing Officer Robert Finigan puts it: "The research confirms that sustainable wellness transformation requires an integrative methodology—harmonizing cutting-edge scientific advances with proven traditional practices to address comprehensive human health needs."
This isn't about choosing between high-tech solutions and natural approaches. It's about intelligently combining them to create something more powerful than either could be alone.
We believe we're standing at the beginning of a new era in personal wellness—one where your unique biological signature, lifestyle, and goals can be seamlessly integrated into a personalized health strategy that actually works for your life.
The crisis is real, but so is the opportunity. With the right combination of scientific innovation, technological advancement, and personalized care, we can reverse these troubling health trends and help people reclaim their vitality.
Want to dive deeper into our research findings?
Learn more about MAKE Wellness and our approach to next-generation health innovation at
